Tag Archives: mdvn

How Much Could Medivation Sell For? Wall Street Speculates

Shares of drugmaker Medivation ( MDVN ) soared more than 20% Thursday to a nearly three-month high on rumors that the company is fending off suitors, leading Wall Street to speculate on how much the company might go for. Late Wednesday, Bloomberg — citing anonymous sources — reported that Medivation hired bankers to defend against takeover interest. Reuters, also citing anonymous sources, said that Medivation had been working with JPMorgan ( JPM ). Medivation stock was up 23% in afternoon trading on the stock market today , near 46. Bloomberg mentioned Sanofi ( SNY ) as a possible buyer. Credit Suisse analyst Vamil Divan wrote in a research note that Sanofi made sense as a buyer, since Medivation’s prostate-cancer treatment Xtandi and its pipeline of other cancer treatments would fit Sanofi’s existing cancer franchise. “We model Medivation worth $55 (per share) to Sanofi ($65 with Sanofi’s 23% tax rate),” Divan wrote. “We see Sanofi’s Taxotere sales force potentially increasing Medivation sales 2% and assume a 20% reduction in Medivation’s R&D and 40% reduction in Medivation’s SG&A (sales, general & administrative expenses). We note a 12% tax-rate benefit over Medivation (23% vs 35%).” Divan added that the greatest synergies would actually come with  AstraZeneca ( AZN ), given its market-leading sales force for its prostate-cancer drug Casodex. He estimated that Medivation would be worth $59 a share to AstraZeneca, or $75 with its 16% tax rate.  Roche ( RHHBY ), which has a cancer franchise but not in prostate, would do well to pay $54 to $60 a share. Jefferies analyst Biren Amin made a similar calculation and came up with a $51-a-share price for Sanofi, and the same for a hypothetical buyout by Bayer ( BAYRY ). He also considered big biotech Amgen ( AMGN ) as a possible buyer, calculating a $54-a-share value to that company. However, Amin also wrote that if the companies adopt a “rose-colored glasses” view of Medivation’s potential, with U.S. Xtandi sales peaking at $5.5 billion, it could be worth $71 a share to Sanofi and Bayer, and $75 to Amgen. Shares of Amgen and Bayer were up a fraction Thursday afternoon, while Sanofi stock was down 1%.

Medivation Stock Hit After Congress Targets Cancer Drug Price

Shares of biotech Medivation ( MDVN ) tumbled Tuesday, a day after Congress attacked the pricing of its lead drug and the company hired a new CFO. Late Monday, the press picked up a letter from six U.S. representatives and six senators, including Democratic presidential candidate Bernard Sanders, to the head of the National Institutes of Health (NIH) urging the agency to exercise its “march-in” right to lower the price of Medivation’s prostate-cancer drug Xtandi. “The 1980 Bayh-Dole Act gives federal agencies, including the NIH, the authority to license a patent when ‘action is necessary to alleviate health or safety needs which are not reasonably satisfied’ or if the invention is not ‘available to the public on reasonable terms,’ ” the letter noted. “Price can be a clear barrier to access for consumers, and despite the law being in place for over 35 years, the NIH has never used this broad and powerful authority to protect consumers from excessive prescription drug prices.” The letter went on to say that Xtandi, which is sold by Medivation’s partner Astellas, costs $129,000 in the U.S. but less than a third of that in Japan, Sweden and Canada. The letter urged the NIH to hold a public hearing on Xtandi and its pricing. A similar hearing in 2004 led Abbott Laboratories ( ABT ) to lower the price of its AIDS drug Norvir for Medicaid and the AIDS Drug Assistance Programs, it said. The NIH did not actually use its march-in authority for that, however, and in 2013 sent a letter to advocates explaining why it thought such a move would be inappropriate. UBS analyst Matthew Roden pointed out that only a minority of Xtandi prescriptions are covered by Medicaid, “though worst case, dual eligibles (i.e. for both Medicare and Medicaid) could be impacted.” Roden estimates that about 75% of Xtandi sales are paid for by Medicare, and perhaps 20% of those are dual eligibles. Is $129,000 A High Price For A New Cancer Drug? The letter represented the latest salvo in politicians’ recent war on high drug prices, and something of a change in focus. While the recent attacks on Valeant Pharmaceuticals ( VRX ) and Turing Pharmaceuticals focused on steep price increases in old, neglected generic drugs, Xtandi is an innovative product that just launched in 2012. Its price is not exceptionally high for a new cancer drug: For instance, Bristol-Myers Squibb ‘s ( BMY ) Opdivo and Merck ‘s ( MRK ) similar drug Keytruda, both launched late in 2014, are going for about $150,000 a year. Meanwhile, Medivation also said late Monday that it had hired Citigroup ( C ) manager Jennifer Jarrett as its new CFO, replacing Rick Bierly who will retire in July. Analyst Roden wrote that Jarrett brings buyout expertise to the company, which may in turn dampen speculation that Medivation itself will be bought. In morning trading on the stock market today , Medivation stock was down 10% near 37. The growth of Xtandi has given the company a healthy IBD EPS Rank of 78, while the stock had been recovering after hitting a two-year low on Feb. 9. It has a weak Relative Strength Rating of just 22, so the stock has performed among the lowest 22% of all stocks over the past 12 months.

Medivation Buying Breast-Cancer Drug From BioMarin

Drugmaker Medivation (MDVN) agreed to acquire a late-stage breast-cancer drug candidate from BioMarin Pharmaceutical (BMRN) Monday in a deal worth up to $570 million. Medivation is paying $410 million upfront for talazoparib, which is currently in phase three testing for advanced or metastatic breast cancer involving germline mutations of the BRCA gene. If the drug succeeds, BioMarin is due up to $160 million in milestone payments along with